[Week 1 schedule | NFL Week 1 live blog]
The late afternoon slate of games for Week 1 has a couple of intriguing matchups, highlighted by a divisional showdown in Green Bay when the Detroit Lions face the Packers. Detroit swept the season series last year, so Green Bay will be looking for revenge during the debut of their newest defensive weapon, former Dallas Cowboy Micah Parsons.
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Detroit is a team that went through major changes during the offseason, losing both coordinators to head coaching jobs. Ben Johnson took his talents to Chicago and will make his first visit to Motown as the opposing coach in Week 2. The Lions struggled through the preseason, going 1-3, causing some to worry. Former DC Aaron Glenn left to coach the NY Jets, so all eyes will be on the Lions’ new coordinators from the first snap.
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Green Bay got a new lease on life last week when they pulled off the trade to acquire Parsons for a couple of (likely late) first-round picks and Pro Bowl defensive tackle Kenny Clark. While Parsons is dealing with a back injury, he is expected to suit up for Week 1 even if it takes an epidural to do so. The Packers seemingly switched out one All-Pro defender for another as they released cornerback Jaire Alexander in the offseason. Packers QB Jordan Love will be under a microscope after having a surgical procedure on his left thumb recently.
Schedule, TV channels for Week 1 afternoon games
All times listed are ET*
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Tennessee Titans at Denver Broncos, 4:05 p.m. on Fox
San Francisco 49ers at Seattle Seahawks, 4:05 p.m. on Fox
Detroit Lions at Green Bay Packers, 4:25 p.m. on CBS
Houston Texans at Los Angeles Rams, 4:25 p.m. on CBS
NFL Week 1 live blog
Follow along with Yahoo Sports for live updates, highlights and more from the afternoon game slate for Week 1 of the 2025 NFL season: